Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 3037651..3038150 Replicon chromosome
Accession NZ_CP113808
Organism Shewanella sp. DAU305

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag OX890_RS12790 Protein ID WP_197721134.1
Coordinates 3037651..3037821 (+) Length 57 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag OX890_RS12795 Protein ID WP_126491952.1
Coordinates 3037818..3038150 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OX890_RS12775 (OX890_12775) 3034590..3035195 + 606 WP_006086154.1 DUF998 domain-containing protein -
OX890_RS12780 (OX890_12780) 3035351..3036034 + 684 WP_126491951.1 hypothetical protein -
OX890_RS12785 (OX890_12785) 3036126..3037225 - 1100 Protein_2467 reverse transcriptase domain-containing protein -
OX890_RS12790 (OX890_12790) 3037651..3037821 + 171 WP_197721134.1 type II toxin-antitoxin system HicA family toxin Toxin
OX890_RS12795 (OX890_12795) 3037818..3038150 + 333 WP_126491952.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
OX890_RS12800 (OX890_12800) 3038725..3039153 - 429 WP_126491953.1 hypothetical protein -
OX890_RS12805 (OX890_12805) 3039311..3039881 + 571 Protein_2471 transposase -
OX890_RS12810 (OX890_12810) 3040219..3040707 + 489 WP_126491954.1 hypothetical protein -
OX890_RS12815 (OX890_12815) 3040896..3041849 + 954 WP_268649340.1 hypothetical protein -
OX890_RS12820 (OX890_12820) 3041836..3042825 + 990 WP_126491956.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(2-47)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 57 a.a.        Molecular weight: 6418.34 Da        Isoelectric Point: 8.8787

>T266071 WP_197721134.1 NZ_CP113808:3037651-3037821 [Shewanella sp. DAU305]
MFKALGADVSERAGSRVAVVLFDEVRVFHRPHPSPNTDKRAITSIWKWLEENEVKP

Download         Length: 171 bp

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12343.08 Da        Isoelectric Point: 8.9218

>AT266071 WP_126491952.1 NZ_CP113808:3037818-3038150 [Shewanella sp. DAU305]
MNIMVVDGYKAKIEYDPQLDQFRGEILGLNGSADFYGTNPASLRREFKNSLKVFLEVCKEKGIKPSKEFSGKFNLRIPPH
LHAEVAARASAEGKSINQWVSEVLRNSVSE

Download         Length: 333 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References