Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 2927474..2928426 Replicon chromosome
Accession NZ_CP113798
Organism Rhodococcus pyridinivorans strain P23

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag OQN32_RS13480 Protein ID WP_159418169.1
Coordinates 2927474..2928043 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag OQN32_RS13485 Protein ID WP_120282896.1
Coordinates 2928040..2928426 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQN32_RS13460 (OQN32_13460) 2922655..2923770 + 1116 WP_159418172.1 FAD-dependent monooxygenase -
OQN32_RS13465 (OQN32_13465) 2923814..2924761 + 948 WP_268653750.1 alpha/beta hydrolase -
OQN32_RS13470 (OQN32_13470) 2924754..2925692 + 939 WP_120282890.1 MBL fold metallo-hydrolase -
OQN32_RS13475 (OQN32_13475) 2925718..2927442 + 1725 WP_120282892.1 CocE/NonD family hydrolase -
OQN32_RS13480 (OQN32_13480) 2927474..2928043 - 570 WP_159418169.1 zeta toxin family protein Toxin
OQN32_RS13485 (OQN32_13485) 2928040..2928426 - 387 WP_120282896.1 hypothetical protein Antitoxin
OQN32_RS13490 (OQN32_13490) 2928632..2929702 + 1071 WP_159418168.1 class I SAM-dependent methyltransferase -
OQN32_RS13495 (OQN32_13495) 2929772..2930137 + 366 WP_120282900.1 HNH endonuclease -
OQN32_RS13500 (OQN32_13500) 2931534..2932466 - 933 WP_159418167.1 TAXI family TRAP transporter solute-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-67)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20510.63 Da        Isoelectric Point: 10.6895

>T266064 WP_159418169.1 NZ_CP113798:c2928043-2927474 [Rhodococcus pyridinivorans]
MRRLDLIVGPNGSGKSTFVELSLAPLLPRSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEAGFTVVLHVMLVPETMSVLRVQHRVASGGHAVPEDKIRARYRRLWPLVAEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPGALTGLG

Download         Length: 570 bp

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14080.57 Da        Isoelectric Point: 4.7096

>AT266064 WP_120282896.1 NZ_CP113798:c2928426-2928040 [Rhodococcus pyridinivorans]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYVEILAARGVTTVVLDDEGRLVEQRPDGSRRVLDDA

Download         Length: 387 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References