Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1706983..1707557 Replicon chromosome
Accession NZ_CP113797
Organism Leptolyngbya sp. PKUAC-SCTA174

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OXH18_RS07435 Protein ID WP_268611854.1
Coordinates 1707219..1707557 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OXH18_RS07430 Protein ID WP_268611853.1
Coordinates 1706983..1707219 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXH18_RS07390 (OXH18_07390) 1702165..1702332 - 168 WP_268611842.1 hypothetical protein -
OXH18_RS07395 (OXH18_07395) 1702523..1702825 + 303 WP_268611843.1 hypothetical protein -
OXH18_RS07400 (OXH18_07400) 1702813..1703049 + 237 WP_268611845.1 hypothetical protein -
OXH18_RS07405 (OXH18_07405) 1703182..1703679 - 498 WP_268611846.1 DUF3368 domain-containing protein -
OXH18_RS07410 (OXH18_07410) 1703676..1703921 - 246 WP_268611848.1 UPF0175 family protein -
OXH18_RS07415 (OXH18_07415) 1704195..1704842 + 648 WP_268611850.1 HNH endonuclease -
OXH18_RS07420 (OXH18_07420) 1705008..1705817 + 810 WP_268611851.1 SDR family oxidoreductase -
OXH18_RS07425 (OXH18_07425) 1705972..1706724 + 753 WP_268611852.1 nitroreductase family protein -
OXH18_RS07430 (OXH18_07430) 1706983..1707219 + 237 WP_268611853.1 hypothetical protein Antitoxin
OXH18_RS07435 (OXH18_07435) 1707219..1707557 + 339 WP_268611854.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OXH18_RS07440 (OXH18_07440) 1707750..1707941 - 192 WP_268611855.1 hypothetical protein -
OXH18_RS07445 (OXH18_07445) 1708111..1708416 + 306 WP_268613141.1 c-type cytochrome -
OXH18_RS07450 (OXH18_07450) 1708555..1708902 - 348 WP_268611857.1 hypothetical protein -
OXH18_RS07455 (OXH18_07455) 1709066..1710727 - 1662 WP_268611858.1 glycosyltransferase family 39 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-109)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12651.55 Da        Isoelectric Point: 4.5702

>T266062 WP_268611854.1 NZ_CP113797:1707219-1707557 [Leptolyngbya sp. PKUAC-SCTA174]
MYRGEIWWANLPNPVGSEPGYRRPVLVIQDDTFTQSRIRTIIVVIITSNVQLAEAPGNVLLPREVSGLPRDSVVNISQIF
TVNKTFLVERVGALPDYLQEEVDEGLRTILYL

Download         Length: 339 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9112.47 Da        Isoelectric Point: 6.2819

>AT266062 WP_268611853.1 NZ_CP113797:1706983-1707219 [Leptolyngbya sp. PKUAC-SCTA174]
MKTAISLPDSVFEQAEALAQQLGLSRSELYTKALQAYLKRYNRDQILLKLNQVYSRESSELDPVMARMQFMSLPREDW

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References