Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2020253..2020397 Replicon chromosome
Accession NZ_CP113789
Organism Klebsiella variicola subsp. tropica strain BSK_177V2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2020289..2020391 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2020253..2020397 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OUI59_RS09975 (OUI59_09975) 2015383..2017443 + 2061 WP_100630720.1 oligopeptidase B -
OUI59_RS09980 (OUI59_09980) 2017447..2018106 - 660 WP_074385460.1 exodeoxyribonuclease X -
OUI59_RS09985 (OUI59_09985) 2018185..2018415 - 231 WP_012541260.1 DNA polymerase III subunit theta -
OUI59_RS09990 (OUI59_09990) 2018529..2018903 + 375 WP_268657794.1 CopC domain-containing protein YobA -
OUI59_RS09995 (OUI59_09995) 2018907..2019776 + 870 WP_268657795.1 copper homeostasis membrane protein CopD -
OUI59_RS10000 (OUI59_10000) 2019793..2020131 + 339 WP_008804271.1 YebY family protein -
- 2020253..2020397 - 145 - - Antitoxin
- 2020289..2020391 + 103 - - Toxin
OUI59_RS10005 (OUI59_10005) 2020776..2020919 - 144 WP_142667623.1 Ecr family regulatory small membrane protein -
OUI59_RS10010 (OUI59_10010) 2021023..2021991 - 969 WP_268657796.1 VirK/YbjX family protein -
OUI59_RS10015 (OUI59_10015) 2022148..2022801 + 654 WP_268657797.1 protein-serine/threonine phosphatase -
OUI59_RS10020 (OUI59_10020) 2022798..2022989 - 192 WP_002911395.1 YebW family protein -
OUI59_RS10025 (OUI59_10025) 2023087..2023326 - 240 WP_002911393.1 YebV family protein -
OUI59_RS10030 (OUI59_10030) 2023442..2024875 - 1434 WP_074385464.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266049 NZ_CP113789:2020289-2020391 [Klebsiella variicola subsp. tropica]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT266049 NZ_CP113789:c2020397-2020253 [Klebsiella variicola subsp. tropica]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References