Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4131145..4131661 Replicon chromosome
Accession NZ_CP113541
Organism Salmonella enterica strain CHC

Toxin (Protein)


Gene name relE Uniprot ID C0Q7A9
Locus tag OXV05_RS19910 Protein ID WP_000220578.1
Coordinates 4131145..4131429 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag OXV05_RS19915 Protein ID WP_000212724.1
Coordinates 4131419..4131661 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV05_RS19895 (4126357) 4126357..4128009 + 1653 WP_000155057.1 alpha,alpha-phosphotrehalase -
OXV05_RS19900 (4128418) 4128418..4130556 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
OXV05_RS19905 (4130677) 4130677..4131141 + 465 WP_001268859.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
OXV05_RS19910 (4131145) 4131145..4131429 - 285 WP_000220578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXV05_RS19915 (4131419) 4131419..4131661 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OXV05_RS19920 (4131739) 4131739..4133652 - 1914 WP_001212137.1 BglG family transcription antiterminator -
OXV05_RS19925 (4133669) 4133669..4134409 - 741 WP_000779263.1 KDGP aldolase family protein -
OXV05_RS19930 (4134406) 4134406..4135524 - 1119 WP_001139182.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
OXV05_RS19935 (4135508) 4135508..4136641 - 1134 WP_000459930.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10854.67 Da        Isoelectric Point: 10.0482

>T266021 WP_000220578.1 NZ_CP113541:c4131429-4131145 [Salmonella enterica]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT266021 WP_000212724.1 NZ_CP113541:c4131661-4131419 [Salmonella enterica]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E876

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References