Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 868199..868859 Replicon chromosome
Accession NZ_CP113541
Organism Salmonella enterica strain CHC

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag OXV05_RS04155 Protein ID WP_000244756.1
Coordinates 868446..868859 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OXV05_RS04150 Protein ID WP_000351186.1
Coordinates 868199..868465 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV05_RS04130 (864127) 864127..865560 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
OXV05_RS04135 (865719) 865719..866030 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OXV05_RS04140 (866194) 866194..866853 + 660 WP_000250289.1 hemolysin III family protein -
OXV05_RS04145 (866969) 866969..867949 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
OXV05_RS04150 (868199) 868199..868465 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OXV05_RS04155 (868446) 868446..868859 + 414 WP_000244756.1 protein YgfX Toxin
OXV05_RS04160 (868912) 868912..869433 - 522 WP_001055885.1 flavodoxin FldB -
OXV05_RS04165 (869546) 869546..870442 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OXV05_RS04170 (870466) 870466..871179 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OXV05_RS04175 (871185) 871185..872918 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T266009 WP_000244756.1 NZ_CP113541:868446-868859 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT266009 WP_000351186.1 NZ_CP113541:868199-868465 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References