265982

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4111006..4111522 Replicon chromosome
Accession NZ_CP113539
Organism Salmonella enterica strain FFL

Toxin (Protein)


Gene name relE Uniprot ID A0A5I6CHB9
Locus tag OXV09_RS19890 Protein ID WP_000220581.1
Coordinates 4111006..4111290 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag OXV09_RS19895 Protein ID WP_000212724.1
Coordinates 4111280..4111522 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV09_RS19875 (4106218) 4106218..4107870 + 1653 WP_023257400.1 alpha,alpha-phosphotrehalase -
OXV09_RS19880 (4108279) 4108279..4110417 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
OXV09_RS19885 (4110538) 4110538..4111002 + 465 WP_001268859.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
OXV09_RS19890 (4111006) 4111006..4111290 - 285 WP_000220581.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXV09_RS19895 (4111280) 4111280..4111522 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OXV09_RS19900 (4111600) 4111600..4113513 - 1914 WP_001212148.1 BglG family transcription antiterminator -
OXV09_RS19905 (4113530) 4113530..4114270 - 741 WP_023229489.1 KDGP aldolase family protein -
OXV09_RS19910 (4114267) 4114267..4115385 - 1119 WP_023256352.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
OXV09_RS19915 (4115369) 4115369..4116502 - 1134 WP_023257225.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10868.70 Da        Isoelectric Point: 10.0482

>T265982 WP_000220581.1 NZ_CP113539:c4111290-4111006 [Salmonella enterica]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT265982 WP_000212724.1 NZ_CP113539:c4111522-4111280 [Salmonella enterica]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I6CHB9

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References