Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1985274..1985417 Replicon chromosome
Accession NZ_CP113539
Organism Salmonella enterica strain FFL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1985313..1985415 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1985274..1985417 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV09_RS09480 1981698..1982396 - 699 WP_023255939.1 exodeoxyribonuclease X -
OXV09_RS09485 1982420..1983076 - 657 WP_023245437.1 carbon-nitrogen hydrolase family protein -
OXV09_RS09490 1983184..1983414 - 231 WP_000856224.1 DNA polymerase III subunit theta -
OXV09_RS09495 1983552..1983926 + 375 WP_000168393.1 CopC domain-containing protein YobA -
OXV09_RS09500 1983927..1984802 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
OXV09_RS09505 1984819..1985172 + 354 WP_000722368.1 YebY family protein -
- 1985274..1985417 - 144 - - Antitoxin
- 1985313..1985415 + 103 - - Toxin
OXV09_RS09510 1985555..1986634 - 1080 WP_058107134.1 phage integrase Arm DNA-binding domain-containing protein -
OXV09_RS09515 1986667..1987818 - 1152 Protein_1858 PD-(D/E)XK nuclease-like domain-containing protein -
OXV09_RS09520 1987807..1987998 + 192 Protein_1859 glycoside hydrolase family 19 protein -
OXV09_RS09525 1988052..1988585 + 534 WP_023256014.1 DUF2514 domain-containing protein -
OXV09_RS09530 1988842..1989009 - 168 WP_000789530.1 lytic enzyme -
OXV09_RS09535 1989074..1989262 - 189 WP_001034748.1 hypothetical protein -
OXV09_RS09540 1989317..1989577 + 261 Protein_1863 DUF1441 family protein -
OXV09_RS09545 1989579..1989794 + 216 Protein_1864 shikimate transporter -
OXV09_RS09550 1989804..1990091 + 288 Protein_1865 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1962087..2005586 43499


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265973 NZ_CP113539:1985313-1985415 [Salmonella enterica]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT265973 NZ_CP113539:c1985417-1985274 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References