Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4130814..4131330 Replicon chromosome
Accession NZ_CP113538
Organism Salmonella enterica strain XSK

Toxin (Protein)


Gene name relE Uniprot ID C0Q7A9
Locus tag OXV06_RS19915 Protein ID WP_000220578.1
Coordinates 4130814..4131098 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag OXV06_RS19920 Protein ID WP_000212724.1
Coordinates 4131088..4131330 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV06_RS19900 (4126026) 4126026..4127678 + 1653 WP_000155057.1 alpha,alpha-phosphotrehalase -
OXV06_RS19905 (4128087) 4128087..4130225 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
OXV06_RS19910 (4130346) 4130346..4130810 + 465 WP_001268859.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
OXV06_RS19915 (4130814) 4130814..4131098 - 285 WP_000220578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXV06_RS19920 (4131088) 4131088..4131330 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OXV06_RS19925 (4131408) 4131408..4133321 - 1914 WP_001212137.1 BglG family transcription antiterminator -
OXV06_RS19930 (4133338) 4133338..4134078 - 741 WP_000779263.1 KDGP aldolase family protein -
OXV06_RS19935 (4134075) 4134075..4135193 - 1119 WP_001139182.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
OXV06_RS19940 (4135177) 4135177..4136310 - 1134 WP_000459930.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10854.67 Da        Isoelectric Point: 10.0482

>T265965 WP_000220578.1 NZ_CP113538:c4131098-4130814 [Salmonella enterica]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT265965 WP_000212724.1 NZ_CP113538:c4131330-4131088 [Salmonella enterica]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E876

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References