Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 868083..868743 Replicon chromosome
Accession NZ_CP113538
Organism Salmonella enterica strain XSK

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag OXV06_RS04155 Protein ID WP_000244756.1
Coordinates 868330..868743 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OXV06_RS04150 Protein ID WP_000351186.1
Coordinates 868083..868349 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV06_RS04130 (864011) 864011..865444 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
OXV06_RS04135 (865603) 865603..865914 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OXV06_RS04140 (866078) 866078..866737 + 660 WP_000250289.1 hemolysin III family protein -
OXV06_RS04145 (866853) 866853..867833 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
OXV06_RS04150 (868083) 868083..868349 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OXV06_RS04155 (868330) 868330..868743 + 414 WP_000244756.1 protein YgfX Toxin
OXV06_RS04160 (868796) 868796..869317 - 522 WP_001055885.1 flavodoxin FldB -
OXV06_RS04165 (869430) 869430..870326 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OXV06_RS04170 (870350) 870350..871063 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OXV06_RS04175 (871069) 871069..872802 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T265953 WP_000244756.1 NZ_CP113538:868330-868743 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT265953 WP_000351186.1 NZ_CP113538:868083-868349 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References