Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 843521..844181 Replicon chromosome
Accession NZ_CP113537
Organism Salmonella enterica strain YZY

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag OXV04_RS04075 Protein ID WP_000244756.1
Coordinates 843768..844181 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OXV04_RS04070 Protein ID WP_000351186.1
Coordinates 843521..843787 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV04_RS04050 (839450) 839450..840883 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
OXV04_RS04055 (841041) 841041..841352 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OXV04_RS04060 (841516) 841516..842175 + 660 WP_000250289.1 hemolysin III family protein -
OXV04_RS04065 (842291) 842291..843271 - 981 WP_023254245.1 tRNA-modifying protein YgfZ -
OXV04_RS04070 (843521) 843521..843787 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OXV04_RS04075 (843768) 843768..844181 + 414 WP_000244756.1 protein YgfX Toxin
OXV04_RS04080 (844234) 844234..844755 - 522 WP_001055885.1 flavodoxin FldB -
OXV04_RS04085 (844868) 844868..845764 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OXV04_RS04090 (845788) 845788..846501 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OXV04_RS04095 (846507) 846507..848240 + 1734 WP_064012850.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T265937 WP_000244756.1 NZ_CP113537:843768-844181 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT265937 WP_000351186.1 NZ_CP113537:843521-843787 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References