Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4209213..4209729 Replicon chromosome
Accession NZ_CP113536
Organism Salmonella enterica strain ZCX

Toxin (Protein)


Gene name relE Uniprot ID C0Q7A9
Locus tag OXV07_RS20510 Protein ID WP_000220578.1
Coordinates 4209213..4209497 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag OXV07_RS20515 Protein ID WP_000212724.1
Coordinates 4209487..4209729 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV07_RS20495 (4204425) 4204425..4206077 + 1653 WP_000155057.1 alpha,alpha-phosphotrehalase -
OXV07_RS20500 (4206486) 4206486..4208624 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
OXV07_RS20505 (4208745) 4208745..4209209 + 465 WP_001268859.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
OXV07_RS20510 (4209213) 4209213..4209497 - 285 WP_000220578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXV07_RS20515 (4209487) 4209487..4209729 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OXV07_RS20520 (4209807) 4209807..4211720 - 1914 WP_001212137.1 BglG family transcription antiterminator -
OXV07_RS20525 (4211737) 4211737..4212477 - 741 WP_000779263.1 KDGP aldolase family protein -
OXV07_RS20530 (4212474) 4212474..4213592 - 1119 WP_001139187.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
OXV07_RS20535 (4213576) 4213576..4214709 - 1134 WP_000459930.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10854.67 Da        Isoelectric Point: 10.0482

>T265931 WP_000220578.1 NZ_CP113536:c4209497-4209213 [Salmonella enterica]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT265931 WP_000212724.1 NZ_CP113536:c4209729-4209487 [Salmonella enterica]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E876

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References