Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 951047..951707 Replicon chromosome
Accession NZ_CP113535
Organism Salmonella enterica strain ZLQ

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag OXV11_RS04660 Protein ID WP_000244756.1
Coordinates 951294..951707 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OXV11_RS04655 Protein ID WP_000351186.1
Coordinates 951047..951313 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV11_RS04635 (946975) 946975..948408 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
OXV11_RS04640 (948567) 948567..948878 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OXV11_RS04645 (949042) 949042..949701 + 660 WP_000250289.1 hemolysin III family protein -
OXV11_RS04650 (949817) 949817..950797 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
OXV11_RS04655 (951047) 951047..951313 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OXV11_RS04660 (951294) 951294..951707 + 414 WP_000244756.1 protein YgfX Toxin
OXV11_RS04665 (951760) 951760..952281 - 522 WP_001055885.1 flavodoxin FldB -
OXV11_RS04670 (952394) 952394..953290 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OXV11_RS04675 (953314) 953314..954027 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OXV11_RS04680 (954033) 954033..955766 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T265900 WP_000244756.1 NZ_CP113535:951294-951707 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT265900 WP_000351186.1 NZ_CP113535:951047-951313 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References