Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 829677..830337 Replicon chromosome
Accession NZ_CP113534
Organism Salmonella enterica strain ZYX

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag OXV08_RS03985 Protein ID WP_000244756.1
Coordinates 829924..830337 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OXV08_RS03980 Protein ID WP_000351186.1
Coordinates 829677..829943 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV08_RS03960 (825606) 825606..827039 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
OXV08_RS03965 (827197) 827197..827508 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OXV08_RS03970 (827672) 827672..828331 + 660 WP_000250289.1 hemolysin III family protein -
OXV08_RS03975 (828447) 828447..829427 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
OXV08_RS03980 (829677) 829677..829943 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OXV08_RS03985 (829924) 829924..830337 + 414 WP_000244756.1 protein YgfX Toxin
OXV08_RS03990 (830390) 830390..830911 - 522 WP_001055885.1 flavodoxin FldB -
OXV08_RS03995 (831024) 831024..831920 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OXV08_RS04000 (831944) 831944..832657 + 714 WP_064047314.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OXV08_RS04005 (832663) 832663..834396 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T265882 WP_000244756.1 NZ_CP113534:829924-830337 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT265882 WP_000351186.1 NZ_CP113534:829677-829943 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References