Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-phd/RelE(toxin)
Location 82665..83290 Replicon plasmid unnamed
Accession NZ_CP113530
Organism Mycobacterium sp. Aquia_216

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OK015_RS28865 Protein ID WP_268133267.1
Coordinates 82665..82955 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag OK015_RS28870 Protein ID WP_268133269.1
Coordinates 83093..83290 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OK015_RS28845 (OK015_28845) 78188..79102 + 915 WP_268133261.1 alpha/beta fold hydrolase -
OK015_RS28850 (OK015_28850) 79804..81153 + 1350 WP_268133387.1 pyridoxal-dependent decarboxylase -
OK015_RS28855 (OK015_28855) 81216..81998 + 783 WP_268133263.1 PhzF family phenazine biosynthesis protein -
OK015_RS28860 (OK015_28860) 82382..82663 + 282 WP_268133265.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OK015_RS28865 (OK015_28865) 82665..82955 + 291 WP_268133267.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OK015_RS28870 (OK015_28870) 83093..83290 + 198 WP_268133269.1 hypothetical protein Antitoxin
OK015_RS28875 (OK015_28875) 83389..83664 + 276 WP_268133389.1 Fic family protein -
OK015_RS28880 (OK015_28880) 83795..84619 + 825 Protein_79 serine/threonine-protein kinase -
OK015_RS28885 (OK015_28885) 87334..88080 - 747 Protein_80 PE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..113269 113269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10891.48 Da        Isoelectric Point: 10.8110

>T265878 WP_268133267.1 NZ_CP113530:82665-82955 [Mycobacterium sp. Aquia_216]
VAKPGRGYVTGFTATAKRDLDRLPPRILAAVIEFAFGDLACEPRRVGKPLGRDLAGHHGGRRGPYRLLYRIDDETQTIWV
HRVDHRAYVYRPPANR

Download         Length: 291 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 6980.90 Da        Isoelectric Point: 7.0109

>AT265878 WP_268133269.1 NZ_CP113530:83093-83290 [Mycobacterium sp. Aquia_216]
MPALNVDFSDEELAVVRSAASNAGASMRAFAKQAILDKAVDRTGRIHALGQEIAERSAELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References