Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1854371..1855050 Replicon chromosome
Accession NZ_CP113517
Organism Methylomonas rapida strain MP1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NM686_RS08800 Protein ID WP_255187507.1
Coordinates 1854616..1855050 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NM686_RS08795 Protein ID WP_255187506.1
Coordinates 1854371..1854616 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NM686_RS08765 (NM686_008765) 1849656..1850204 + 549 WP_269022943.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
NM686_RS08770 (NM686_008770) 1850204..1851022 + 819 WP_255187501.1 ABC transporter permease -
NM686_RS08775 (NM686_008775) 1851151..1851357 + 207 WP_255187502.1 nucleotidyltransferase domain-containing protein -
NM686_RS08780 (NM686_008780) 1851836..1852855 + 1020 WP_255187503.1 hypothetical protein -
NM686_RS08785 (NM686_008785) 1852980..1853276 + 297 WP_255187504.1 nucleotidyltransferase domain-containing protein -
NM686_RS08790 (NM686_008790) 1853277..1853837 + 561 WP_255187505.1 hypothetical protein -
NM686_RS08795 (NM686_008795) 1854371..1854616 + 246 WP_255187506.1 hypothetical protein Antitoxin
NM686_RS08800 (NM686_008800) 1854616..1855050 + 435 WP_255187507.1 VapC toxin family PIN domain ribonuclease Toxin
NM686_RS08805 (NM686_008805) 1855450..1855677 + 228 WP_255187508.1 hypothetical protein -
NM686_RS08810 (NM686_008810) 1855674..1856069 + 396 WP_255187509.1 type II toxin-antitoxin system VapC family toxin -
NM686_RS08815 (NM686_008815) 1856075..1857394 + 1320 WP_255187510.1 ABC transporter ATP-binding protein -
NM686_RS08820 (NM686_008820) 1857575..1858414 + 840 WP_255187511.1 FkbM family methyltransferase -
NM686_RS08825 (NM686_008825) 1858418..1859233 + 816 WP_255187512.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-140)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15952.34 Da        Isoelectric Point: 6.4814

>T265862 WP_255187507.1 NZ_CP113517:1854616-1855050 [Methylomonas rapida]
MRALLDVNVLIALMDAGHVHHEMAMNWLEKNLSFGWASCPITQNGCIRIMSQPNYPGALPVTQVADRLAEAVASVEHEFW
PDSISLLDSNVFSWSKVLGHRQVTDIYLLTLAVQNGGRFVTLDRRIAFDSVKGASPTQLVHLQA

Download         Length: 435 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8835.99 Da        Isoelectric Point: 9.1060

>AT265862 WP_255187506.1 NZ_CP113517:1854371-1854616 [Methylomonas rapida]
MRTTVDLEDDVLAAAKELARMQNVAVGRVISRLMREALSGQSSLSGTTVESRTVGGFRPFSSRGIVVTNDRVNELRDREG
V

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References