265861

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1412617..1413536 Replicon chromosome
Accession NZ_CP113516
Organism Bacillus paralicheniformis strain 285-3

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A6I7TYV7
Locus tag OU809_RS07130 Protein ID WP_023856735.1
Coordinates 1412790..1413536 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A6I7TM13
Locus tag OU809_RS07125 Protein ID WP_023856734.1
Coordinates 1412617..1412790 (-) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU809_RS07100 (OU809_07100) 1408031..1409128 + 1098 WP_025811596.1 mannonate dehydratase -
OU809_RS07105 (OU809_07105) 1409104..1409952 + 849 WP_023856787.1 SDR family oxidoreductase -
OU809_RS07110 (OU809_07110) 1409978..1411002 + 1025 Protein_1347 zinc-binding alcohol dehydrogenase family protein -
OU809_RS07115 (OU809_07115) 1411054..1412325 + 1272 WP_035338913.1 MFS transporter -
OU809_RS07120 (OU809_07120) 1412392..1412523 - 132 WP_023856733.1 hypothetical protein -
OU809_RS07125 (OU809_07125) 1412617..1412790 - 174 WP_023856734.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OU809_RS07130 (OU809_07130) 1412790..1413536 - 747 WP_023856735.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OU809_RS07135 (OU809_07135) 1413646..1414644 - 999 WP_023856736.1 inorganic phosphate transporter -
OU809_RS07140 (OU809_07140) 1414657..1415274 - 618 WP_023856737.1 DUF47 domain-containing protein -
OU809_RS07145 (OU809_07145) 1415607..1417364 + 1758 WP_023856738.1 gamma-glutamyltransferase -
OU809_RS07150 (OU809_07150) 1417499..1418143 + 645 WP_003180888.1 YesL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29421.87 Da        Isoelectric Point: 4.6015

>T265861 WP_023856735.1 NZ_CP113516:c1413536-1412790 [Bacillus paralicheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEDGDD

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6897.99 Da        Isoelectric Point: 10.8356

>AT265861 WP_023856734.1 NZ_CP113516:c1412790-1412617 [Bacillus paralicheniformis]
MEPAFQQDHESAKKRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6I7TYV7

Antitoxin

Source ID Structure
AlphaFold DB A0A6I7TM13

References