265859

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 3678908..3679825 Replicon chromosome
Accession NZ_CP113515
Organism Bacillus sp. KICET-1

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag OVA33_RS18310 Protein ID WP_007407256.1
Coordinates 3678908..3679654 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag OVA33_RS18315 Protein ID WP_003154807.1
Coordinates 3679655..3679825 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OVA33_RS18290 (3674301) 3674301..3675251 - 951 WP_007610844.1 ring-cleaving dioxygenase -
OVA33_RS18295 (3675573) 3675573..3676889 + 1317 WP_063636817.1 amino acid permease -
OVA33_RS18300 (3677176) 3677176..3677793 + 618 WP_003154804.1 DUF47 domain-containing protein -
OVA33_RS18305 (3677806) 3677806..3678804 + 999 WP_017417610.1 inorganic phosphate transporter -
OVA33_RS18310 (3678908) 3678908..3679654 + 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OVA33_RS18315 (3679655) 3679655..3679825 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OVA33_RS18320 (3679922) 3679922..3680047 + 126 WP_003154809.1 hypothetical protein -
OVA33_RS18325 (3680082) 3680082..3680960 - 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
OVA33_RS18330 (3680974) 3680974..3681237 - 264 WP_003154813.1 phage holin -
OVA33_RS18335 (3681251) 3681251..3681514 - 264 WP_021493821.1 hemolysin XhlA family protein -
OVA33_RS18340 (3681566) 3681566..3682327 - 762 WP_063636818.1 hypothetical protein -
OVA33_RS18345 (3682384) 3682384..3682581 - 198 WP_007610833.1 XkdX family protein -
OVA33_RS18350 (3682586) 3682586..3682957 - 372 WP_038457736.1 XkdW family protein -
OVA33_RS18355 (3682970) 3682970..3683332 - 363 WP_014721043.1 hypothetical protein -
OVA33_RS18360 (3683443) 3683443..3683994 - 552 Protein_3571 terminase -
OVA33_RS18365 (3684107) 3684107..3684619 - 513 WP_017417605.1 sigma-70 family RNA polymerase sigma factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T265859 WP_007407256.1 NZ_CP113515:3678908-3679654 [Bacillus sp. KICET-1]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT265859 WP_003154807.1 NZ_CP113515:3679655-3679825 [Bacillus sp. KICET-1]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References