265857

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4792732..4793267 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag OWC53_RS21980 Protein ID WP_015842269.1
Coordinates 4792980..4793267 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag OWC53_RS21975 Protein ID WP_010281712.1
Coordinates 4792732..4792983 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS21945 (OWC53_21930) 4788170..4788496 + 327 WP_014913674.1 helix-turn-helix domain-containing protein -
OWC53_RS21950 (OWC53_21935) 4788481..4788795 + 315 WP_039528006.1 HipA N-terminal domain-containing protein -
OWC53_RS21955 (OWC53_21940) 4788792..4789832 + 1041 WP_268197954.1 HipA domain-containing protein -
OWC53_RS21960 (OWC53_21945) 4789892..4790515 - 624 WP_039284934.1 LysE family translocator -
OWC53_RS21965 (OWC53_21950) 4790783..4791538 + 756 WP_110163156.1 thiol:disulfide interchange protein DsbG -
OWC53_RS21970 (OWC53_21955) 4791572..4792477 - 906 WP_268197955.1 siderophore-interacting protein -
OWC53_RS21975 (OWC53_21960) 4792732..4792983 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OWC53_RS21980 (OWC53_21965) 4792980..4793267 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OWC53_RS21985 (OWC53_21970) 4793371..4794723 - 1353 WP_205559960.1 glutathione-disulfide reductase -
OWC53_RS21990 (OWC53_21975) 4794852..4795694 - 843 WP_039498363.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
OWC53_RS21995 (OWC53_21980) 4795845..4796642 + 798 WP_268197956.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T265857 WP_015842269.1 NZ_CP113504:4792980-4793267 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT265857 WP_010281712.1 NZ_CP113504:4792732-4792983 [Pectobacterium brasiliense]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References