Detailed information of TA system TA265855

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 4714931..4716371
• Replicon: chromosome
• Accession: NZ_CP113504
• Organism: Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: OWC53_RS21620
• Protein ID: WP_268197927.1
• Coordinates: 4714931..4715818 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: OWC53_RS21625
• Protein ID: WP_039498424.1
• Coordinates: 4715847..4716371 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OWC53_RS21600 (OWC53_21585)	4710921..4711742	+	822	WP_268198906.1	M55 family metallopeptidase	-
OWC53_RS21605 (OWC53_21590)	4711801..4712748	+	948	WP_010284276.1	isoaspartyl peptidase/L-asparaginase	-
OWC53_RS21610 (OWC53_21595)	4712961..4713869	+	909	WP_014913736.1	LysR family transcriptional regulator	-
OWC53_RS21615 (OWC53_21600)	4713968..4714831	+	864	WP_010300687.1	YicC/YloC family endoribonuclease	-
OWC53_RS21620 (OWC53_21605)	4714931..4715818	-	888	WP_268197927.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
OWC53_RS21625 (OWC53_21610)	4715847..4716371	-	525	WP_039498424.1	hypothetical protein	Antitoxin
OWC53_RS21630 (OWC53_21615)	4716703..4719192	-	2490	WP_268197928.1	restriction endonuclease-like protein	-
OWC53_RS21635 (OWC53_21620)	4719211..4721061	-	1851	WP_268197929.1	DUF3578 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-269)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34230.21 Da
• Isoelectric Point: 6.1750

>T265855 WP_268197927.1 NZ_CP113504:c4715818-4714931 [Pectobacterium brasiliense]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGERQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERALDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG

Nucleotide

• Length: 888 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19446.55 Da
• Isoelectric Point: 9.0504

>AT265855 WP_039498424.1 NZ_CP113504:c4716371-4715847 [Pectobacterium brasiliense]
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFETPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp