Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 1083957..1084993 | Replicon | chromosome |
| Accession | NZ_CP113504 | ||
| Organism | Pectobacterium brasiliense strain 21PCA_AGRO2 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | OWC53_RS05030 | Protein ID | WP_234405985.1 |
| Coordinates | 1084490..1084993 (+) | Length | 168 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | OWC53_RS05025 | Protein ID | WP_119871525.1 |
| Coordinates | 1083957..1084418 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OWC53_RS05005 (OWC53_05000) | 1079018..1079551 | + | 534 | WP_010282870.1 | RNA pyrophosphohydrolase | - |
| OWC53_RS05010 (OWC53_05005) | 1079564..1081810 | + | 2247 | WP_039283946.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| OWC53_RS05015 (OWC53_05010) | 1082037..1082903 | + | 867 | WP_010286783.1 | prolipoprotein diacylglyceryl transferase | - |
| OWC53_RS05020 (OWC53_05015) | 1082940..1083734 | + | 795 | WP_039312476.1 | thymidylate synthase | - |
| OWC53_RS05025 (OWC53_05020) | 1083957..1084418 | + | 462 | WP_119871525.1 | helix-turn-helix domain-containing protein | Antitoxin |
| OWC53_RS05030 (OWC53_05025) | 1084490..1084993 | + | 504 | WP_234405985.1 | PIN domain-containing protein | Toxin |
| OWC53_RS05035 (OWC53_05030) | 1085173..1085676 | + | 504 | WP_268198387.1 | prepilin peptidase-dependent protein | - |
| OWC53_RS05040 (OWC53_05035) | 1085685..1086296 | + | 612 | WP_268198847.1 | prepilin peptidase-dependent protein | - |
| OWC53_RS05045 (OWC53_05040) | 1086293..1086748 | + | 456 | WP_268198388.1 | YgdB family protein | - |
| OWC53_RS05050 (OWC53_05045) | 1086735..1087130 | + | 396 | WP_039525072.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 168 a.a. Molecular weight: 18754.62 Da Isoelectric Point: 4.6914
>T265850 WP_234405985.1 NZ_CP113504:1084490-1084993 [Pectobacterium brasiliense]
MHLGLTGLYQPKWTALIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGFEQLIPALVLPDADDRHVLAAAIRA
NAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRKPPFDVDEYLDCLLRQGLPMTVKEL
DAYRALI
MHLGLTGLYQPKWTALIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGFEQLIPALVLPDADDRHVLAAAIRA
NAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRKPPFDVDEYLDCLLRQGLPMTVKEL
DAYRALI
Download Length: 504 bp
Antitoxin
Download Length: 154 a.a. Molecular weight: 17277.78 Da Isoelectric Point: 6.2253
>AT265850 WP_119871525.1 NZ_CP113504:1083957-1084418 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY
Download Length: 462 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|