265849

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1057096..1057622 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag OWC53_RS04880 Protein ID WP_268198382.1
Coordinates 1057096..1057401 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID E0SK21
Locus tag OWC53_RS04885 Protein ID WP_012773205.1
Coordinates 1057404..1057622 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS04870 (OWC53_04865) 1053756..1056413 - 2658 WP_080163925.1 hypothetical protein -
OWC53_RS04875 (OWC53_04870) 1056542..1056898 - 357 WP_080163924.1 hypothetical protein -
OWC53_RS04880 (OWC53_04875) 1057096..1057401 - 306 WP_268198382.1 type II toxin-antitoxin system toxin CcdB Toxin
OWC53_RS04885 (OWC53_04880) 1057404..1057622 - 219 WP_012773205.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
OWC53_RS04890 (OWC53_04885) 1057681..1058424 - 744 WP_080163920.1 MobC family replication-relaxation protein -
OWC53_RS04895 (OWC53_04890) 1058566..1058736 + 171 WP_155121810.1 hypothetical protein -
OWC53_RS04900 (OWC53_04895) 1059328..1059669 - 342 WP_039309297.1 hypothetical protein -
OWC53_RS04905 (OWC53_04900) 1059855..1060049 + 195 WP_080163917.1 YlcI/YnfO family protein -
OWC53_RS04910 (OWC53_04905) 1060156..1061415 - 1260 WP_268198383.1 integrase arm-type DNA-binding domain-containing protein -
OWC53_RS04920 (OWC53_04915) 1061965..1062096 + 132 WP_258069300.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1053099..1061593 8494


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11702.64 Da        Isoelectric Point: 4.8382

>T265849 WP_268198382.1 NZ_CP113504:c1057401-1057096 [Pectobacterium brasiliense]
MQFIVYLYKRASHYKMFVDVQSDIVDTPKRRMVIPLIESHHLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEVI
TDLGDCADEIKDALNLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8201.16 Da        Isoelectric Point: 7.2038

>AT265849 WP_012773205.1 NZ_CP113504:c1057622-1057404 [Pectobacterium brasiliense]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB E0SK21

References