Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 828429..829089 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OWC53_RS03895 Protein ID WP_010301815.1
Coordinates 828715..829089 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag OWC53_RS03890 Protein ID WP_005971623.1
Coordinates 828429..828695 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS03870 (OWC53_03865) 824255..825259 - 1005 WP_039555591.1 substrate-binding domain-containing protein -
OWC53_RS03875 (OWC53_03870) 825314..825922 - 609 WP_039502189.1 HD domain-containing protein -
OWC53_RS03880 (OWC53_03875) 826354..827001 + 648 WP_010279833.1 hemolysin III family protein -
OWC53_RS03885 (OWC53_03880) 827192..828193 - 1002 WP_268198304.1 tRNA-modifying protein YgfZ -
OWC53_RS03890 (OWC53_03885) 828429..828695 + 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
OWC53_RS03895 (OWC53_03890) 828715..829089 + 375 WP_010301815.1 protein YgfX Toxin
OWC53_RS03900 (OWC53_03895) 829158..830093 + 936 WP_010301818.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
OWC53_RS03905 (OWC53_03900) 830159..830482 - 324 WP_268198305.1 hypothetical protein -
OWC53_RS03910 (OWC53_03905) 830511..831029 - 519 WP_014914178.1 flavodoxin FldB -
OWC53_RS03915 (OWC53_03910) 831373..831759 - 387 WP_039282122.1 thioesterase family protein -
OWC53_RS03920 (OWC53_03915) 831964..833292 - 1329 WP_010279860.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-119)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14654.33 Da        Isoelectric Point: 10.5560

>T265847 WP_010301815.1 NZ_CP113504:828715-829089 [Pectobacterium brasiliense]
MQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 375 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT265847 WP_005971623.1 NZ_CP113504:828429-828695 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References