Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 763497..764222 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag OWC53_RS03580 Protein ID WP_268198283.1
Coordinates 763902..764222 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag OWC53_RS03575 Protein ID WP_268198282.1
Coordinates 763497..763832 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS03545 (OWC53_03540) 759117..760148 + 1032 WP_268198278.1 hypothetical protein -
OWC53_RS03550 (OWC53_03545) 760244..761131 + 888 WP_268198279.1 50S ribosome-binding GTPase -
OWC53_RS03555 (OWC53_03550) 761315..761473 + 159 WP_155242703.1 hypothetical protein -
OWC53_RS03560 (OWC53_03555) 761620..762453 + 834 WP_268198280.1 hypothetical protein -
OWC53_RS03565 (OWC53_03560) 762511..762861 + 351 WP_113631700.1 hypothetical protein -
OWC53_RS03570 (OWC53_03565) 762984..763457 + 474 WP_268198281.1 DNA repair protein RadC -
OWC53_RS03575 (OWC53_03570) 763497..763832 + 336 WP_268198282.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
OWC53_RS03580 (OWC53_03575) 763902..764222 + 321 WP_268198283.1 TA system toxin CbtA family protein Toxin
OWC53_RS03585 (OWC53_03580) 764340..765173 + 834 WP_268198841.1 DUF4942 domain-containing protein -
OWC53_RS03590 (OWC53_03585) 765582..765740 - 159 Protein_698 NADP-dependent oxidoreductase -
OWC53_RS03595 (OWC53_03590) 765716..766105 - 390 WP_268198284.1 hypothetical protein -
OWC53_RS03600 (OWC53_03595) 766343..766978 - 636 WP_268198285.1 hypothetical protein -
OWC53_RS03605 (OWC53_03600) 767311..767730 - 420 Protein_701 lysozyme -
OWC53_RS03610 (OWC53_03605) 767723..767939 - 217 Protein_702 hypothetical protein -
OWC53_RS03615 (OWC53_03610) 768437..768856 + 420 WP_240559198.1 hypothetical protein -
OWC53_RS03620 (OWC53_03615) 768898..769050 + 153 WP_230857215.1 LuxR C-terminal-related transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11991.72 Da        Isoelectric Point: 5.0492

>T265846 WP_268198283.1 NZ_CP113504:763902-764222 [Pectobacterium brasiliense]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12380.16 Da        Isoelectric Point: 5.8342

>AT265846 WP_268198282.1 NZ_CP113504:763497-763832 [Pectobacterium brasiliense]
MSSIEAPEWGLKCTVTPRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQGCIT
LYCNAWTCEADTLGSVGYVYIAIYPSSSTAE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References