Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 375046..375577 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag OWC53_RS01735 Protein ID WP_039282785.1
Coordinates 375290..375577 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag OWC53_RS01730 Protein ID WP_039282788.1
Coordinates 375046..375300 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS01710 (OWC53_01710) 370913..371800 + 888 WP_014913881.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
OWC53_RS01720 (OWC53_01720) 372251..373444 - 1194 WP_039282790.1 IS4 family transposase -
OWC53_RS01725 (OWC53_01725) 373613..374818 + 1206 WP_075277970.1 ISL3 family transposase -
OWC53_RS01730 (OWC53_01730) 375046..375300 + 255 WP_039282788.1 plasmid stabilization protein Antitoxin
OWC53_RS01735 (OWC53_01735) 375290..375577 + 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OWC53_RS01740 (OWC53_01740) 375754..376539 + 786 WP_039499670.1 4,5-DOPA dioxygenase extradiol -
OWC53_RS01745 (OWC53_01745) 376725..377885 - 1161 WP_010297418.1 glutathionylspermidine synthase family protein -
OWC53_RS01750 (OWC53_01750) 377897..378571 - 675 WP_010280216.1 DUF1190 family protein -
OWC53_RS01755 (OWC53_01755) 378990..380381 - 1392 WP_205557405.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 372251..373444 1193


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T265840 WP_039282785.1 NZ_CP113504:375290-375577 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT265840 WP_039282788.1 NZ_CP113504:375046-375300 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References