Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 787684..788245 Replicon chromosome
Accession NZ_CP113500
Organism Mycoplasma feriruminatoris strain L15568

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI15568_RS03425 Protein ID WP_278307858.1
Coordinates 787684..787980 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI15568_RS03430 Protein ID WP_008362623.1
Coordinates 787973..788245 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI15568_RS03405 (MFERI15568_00677) 782784..783413 + 630 WP_278299862.1 beta-phosphoglucomutase -
MFERI15568_RS03410 (MFERI15568_00678) 783520..785196 + 1677 WP_278307856.1 LppA family lipoprotein -
MFERI15568_RS03415 (MFERI15568_00679) 785224..786105 - 882 WP_278287772.1 Cof-type HAD-IIB family hydrolase -
MFERI15568_RS03420 (MFERI15568_00680) 786354..787649 + 1296 WP_278307857.1 ATP-binding protein -
MFERI15568_RS03425 (MFERI15568_00681) 787684..787980 - 297 WP_278307858.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI15568_RS03430 (MFERI15568_00682) 787973..788245 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI15568_RS03435 (MFERI15568_00683) 788429..789598 - 1170 WP_278307859.1 site-specific DNA-methyltransferase -
MFERI15568_RS03440 (MFERI15568_00684) 789758..792868 - 3111 WP_278307860.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11498.45 Da        Isoelectric Point: 9.8106

>T265811 WP_278307858.1 NZ_CP113500:c787980-787684 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSLTGIYKEYRECHIDPDFLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265811 WP_008362623.1 NZ_CP113500:c788245-787973 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References