265809

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 786398..786959 Replicon chromosome
Accession NZ_CP113498
Organism Mycoplasma feriruminatoris strain L15181

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI15181_RS03420 Protein ID WP_278299865.1
Coordinates 786398..786694 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI15181_RS03425 Protein ID WP_008362623.1
Coordinates 786687..786959 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI15181_RS03405 (MFERI15181_00676) 782237..783910 + 1674 WP_278299863.1 LppA family lipoprotein -
MFERI15181_RS03410 (MFERI15181_00677) 783938..784819 - 882 WP_278287772.1 Cof-type HAD-IIB family hydrolase -
MFERI15181_RS03415 (MFERI15181_00678) 785068..786363 + 1296 WP_278299864.1 ATP-binding protein -
MFERI15181_RS03420 (MFERI15181_00679) 786398..786694 - 297 WP_278299865.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI15181_RS03425 (MFERI15181_00680) 786687..786959 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI15181_RS03430 (MFERI15181_00681) 787143..788117 - 975 WP_278300168.1 site-specific DNA-methyltransferase -
MFERI15181_RS03435 (MFERI15181_00683) 788467..791604 - 3138 WP_278299866.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11498.45 Da        Isoelectric Point: 9.8106

>T265809 WP_278299865.1 NZ_CP113498:c786694-786398 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSFTGIYKEYRECHIDPDLLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265809 WP_008362623.1 NZ_CP113498:c786959-786687 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References