Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 792812..793373 Replicon chromosome
Accession NZ_CP113497
Organism Mycoplasma feriruminatoris strain L14815

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI14815_RS03430 Protein ID WP_278287774.1
Coordinates 792812..793108 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI14815_RS03435 Protein ID WP_008362623.1
Coordinates 793101..793373 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI14815_RS03415 (MFERI14815_00682) 788651..790324 + 1674 WP_278288780.1 LppA family lipoprotein -
MFERI14815_RS03420 (MFERI14815_00683) 790352..791233 - 882 WP_278288311.1 Cof-type HAD-IIB family hydrolase -
MFERI14815_RS03425 (MFERI14815_00684) 791482..792777 + 1296 WP_278288781.1 ATP-binding protein -
MFERI14815_RS03430 (MFERI14815_00685) 792812..793108 - 297 WP_278287774.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI14815_RS03435 (MFERI14815_00686) 793101..793373 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI14815_RS03440 (MFERI14815_00687) 793557..794726 - 1170 WP_278288782.1 site-specific DNA-methyltransferase -
MFERI14815_RS03445 (MFERI14815_00688) 794716..795360 - 645 WP_278288783.1 ApaLI family restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11452.38 Da        Isoelectric Point: 9.8106

>T265808 WP_278287774.1 NZ_CP113497:c793108-792812 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILTQGKELDAKYQDHSLTGIYKEYRECHIDPDLLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265808 WP_008362623.1 NZ_CP113497:c793373-793101 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References