Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 791655..792261 Replicon chromosome
Accession NZ_CP113496
Organism Mycoplasma feriruminatoris strain L13461

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI13461_RS03435 Protein ID WP_278299456.1
Coordinates 791655..791996 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI13461_RS03440 Protein ID WP_008362623.1
Coordinates 791989..792261 (-) Length 91 a.a.

Genomic Context


MFERI13461_RS03425MFERI13461_RS03430MFERI13461_RS03420MFERI13461_RS03435MFERI13461_RS03440MFERI13461_RS03445MFERI13461_RS03450
Location: 788882..790177 (1296 bp)
Type: Others
Protein ID: WP_278299455.1
Location: 790246..791658 (1413 bp)
Type: Others
Protein ID: Protein_648
Location: 787752..788633 (882 bp)
Type: Others
Protein ID: WP_278299454.1
Location: 791655..791996 (342 bp)
Type: Toxin
Protein ID: WP_278299456.1
Location: 791989..792261 (273 bp)
Type: Antitoxin
Protein ID: WP_008362623.1
Location: 792445..792570 (126 bp)
Type: Others
Protein ID: WP_278299457.1
Location: 792647..795733 (3087 bp)
Type: Others
Protein ID: WP_278299458.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MFERI13461_RS03420 (MFERI13461_00683)787752..788633-882WP_278299454.1Cof-type HAD-IIB family hydrolase-
MFERI13461_RS03425 (MFERI13461_00684)788882..790177+1296WP_278299455.1ATP-binding protein-
MFERI13461_RS03430790246..791658+1413Protein_648IS3 family transposase-
MFERI13461_RS03435 (MFERI13461_00687)791655..791996-342WP_278299456.1type II toxin-antitoxin system YafQ family toxinToxin
MFERI13461_RS03440 (MFERI13461_00688)791989..792261-273WP_008362623.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
MFERI13461_RS03445792445..792570-126WP_278299457.1hypothetical protein-
MFERI13461_RS03450 (MFERI13461_00690)792647..795733-3087WP_278299458.1ABC transporter substrate-binding protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-91)

Antitoxin

(1-87)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 13114.35 Da        Isoelectric Point: 10.0681

>T265807 WP_278299456.1 NZ_CP113496:c791996-791655 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSLTGIYKEYRECHIDPDFLIYKKDDDKIVIIM
LRLGSHSNLFEKQKTTRLNKKQLPPATINTD

Download         Length: 342 bp


Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265807 WP_008362623.1 NZ_CP113496:c792261-791989 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBL5LA09

References