Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 791655..792261 Replicon chromosome
Accession NZ_CP113496
Organism Mycoplasma feriruminatoris strain L13461

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI13461_RS03435 Protein ID WP_278299456.1
Coordinates 791655..791996 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI13461_RS03440 Protein ID WP_008362623.1
Coordinates 791989..792261 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI13461_RS03420 (MFERI13461_00683) 787752..788633 - 882 WP_278299454.1 Cof-type HAD-IIB family hydrolase -
MFERI13461_RS03425 (MFERI13461_00684) 788882..790177 + 1296 WP_278299455.1 ATP-binding protein -
MFERI13461_RS03430 790246..791658 + 1413 Protein_648 IS3 family transposase -
MFERI13461_RS03435 (MFERI13461_00687) 791655..791996 - 342 WP_278299456.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI13461_RS03440 (MFERI13461_00688) 791989..792261 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI13461_RS03445 792445..792570 - 126 WP_278299457.1 hypothetical protein -
MFERI13461_RS03450 (MFERI13461_00690) 792647..795733 - 3087 WP_278299458.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13114.35 Da        Isoelectric Point: 10.0681

>T265807 WP_278299456.1 NZ_CP113496:c791996-791655 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSLTGIYKEYRECHIDPDFLIYKKDDDKIVIIM
LRLGSHSNLFEKQKTTRLNKKQLPPATINTD

Download         Length: 342 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265807 WP_008362623.1 NZ_CP113496:c792261-791989 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References