Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 784894..785455 Replicon chromosome
Accession NZ_CP113495
Organism Mycoplasma feriruminatoris strain F11561

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MFERI11561_RS03440 Protein ID WP_278288313.1
Coordinates 784894..785190 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID L5LA09
Locus tag MFERI11561_RS03445 Protein ID WP_008362623.1
Coordinates 785183..785455 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFERI11561_RS03425 (MFERI11561_00678) 780766..782406 + 1641 WP_278288310.1 LppA family lipoprotein -
MFERI11561_RS03430 (MFERI11561_00679) 782434..783315 - 882 WP_278288311.1 Cof-type HAD-IIB family hydrolase -
MFERI11561_RS03435 (MFERI11561_00680) 783564..784859 + 1296 WP_278288312.1 ATP-binding protein -
MFERI11561_RS03440 (MFERI11561_00681) 784894..785190 - 297 WP_278288313.1 type II toxin-antitoxin system YafQ family toxin Toxin
MFERI11561_RS03445 (MFERI11561_00682) 785183..785455 - 273 WP_008362623.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MFERI11561_RS03450 (MFERI11561_00683) 785640..786809 - 1170 WP_278288314.1 site-specific DNA-methyltransferase -
MFERI11561_RS03455 (MFERI11561_00684) 786965..790078 - 3114 WP_278288315.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11463.49 Da        Isoelectric Point: 10.0351

>T265806 WP_278288313.1 NZ_CP113495:c785190-784894 [Mycoplasma feriruminatoris]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILIQGKELDAKYQDHSLTGIYKKYRECHIDPDLLIYKKDDDKIVIIM
LRLGSHSNLFEKQKNY

Download         Length: 297 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10257.67 Da        Isoelectric Point: 4.8483

>AT265806 WP_008362623.1 NZ_CP113495:c785455-785183 [Mycoplasma feriruminatoris]
MKTTNLNVRIDKEVKHDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L5LA09

References