Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 528529..528800 Replicon chromosome
Accession NZ_CP113486
Organism Escherichia coli strain GTEN_23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 528567..528670 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 528529..528800 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG550_RS02485 525686..527125 + 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FG550_RS02490 527243..527479 + 237 WP_001295499.1 YebV family protein -
FG550_RS02495 527584..527775 + 192 WP_001296140.1 YebW family protein -
FG550_RS02500 527776..528432 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 528529..528800 + 272 - - Antitoxin
- 528567..528670 - 104 - - Toxin
FG550_RS02505 528828..529169 - 342 WP_000976472.1 YebY family protein -
FG550_RS02510 529182..530054 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
FG550_RS02515 530058..530432 - 375 WP_000168747.1 CopC domain-containing protein YobA -
FG550_RS02520 530571..530801 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FG550_RS02525 530903..531559 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
FG550_RS02530 531583..532245 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 520299..536110 15811


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T265741 NZ_CP113486:c528670-528567 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT265741 NZ_CP113486:528529-528800 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References