Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3336278..3336931 Replicon chromosome
Accession NZ_CP113442
Organism Acinetobacter baumannii strain C9

Toxin (Protein)


Gene name cptA Uniprot ID A0A9E9PBS3
Locus tag OQH41_RS15740 Protein ID WP_002096593.1
Coordinates 3336278..3336667 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OQH41_RS15745 Protein ID WP_001288210.1
Coordinates 3336674..3336931 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQH41_RS15725 (OQH41_15725) 3331396..3333591 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OQH41_RS15730 (OQH41_15730) 3333779..3334345 - 567 WP_000651536.1 rhombosortase -
OQH41_RS15735 (OQH41_15735) 3334423..3335508 - 1086 WP_000049106.1 hypothetical protein -
OQH41_RS15740 (OQH41_15740) 3336278..3336667 - 390 WP_002096593.1 hypothetical protein Toxin
OQH41_RS15745 (OQH41_15745) 3336674..3336931 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OQH41_RS15750 (OQH41_15750) 3337119..3338291 + 1173 WP_001190548.1 acyl-CoA dehydrogenase family protein -
OQH41_RS15755 (OQH41_15755) 3338340..3339830 - 1491 WP_265615263.1 NAD(P)/FAD-dependent oxidoreductase -
OQH41_RS15760 (OQH41_15760) 3340012..3340389 - 378 WP_001216380.1 50S ribosomal protein L17 -
OQH41_RS15765 (OQH41_15765) 3340408..3341415 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15677.99 Da        Isoelectric Point: 10.3890

>T265730 WP_002096593.1 NZ_CP113442:c3336667-3336278 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265730 WP_001288210.1 NZ_CP113442:c3336931-3336674 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References