Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3303402..3303939 Replicon chromosome
Accession NZ_CP113437
Organism Legionella pneumophila strain PATHC007

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OXA90_RS14720 Protein ID WP_042234319.1
Coordinates 3303402..3303698 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OXA90_RS14725 Protein ID WP_027266056.1
Coordinates 3303688..3303939 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXA90_RS14695 (OXA90_14695) 3299612..3300505 - 894 WP_042234326.1 hypothetical protein -
OXA90_RS14700 (OXA90_14700) 3300773..3300964 + 192 WP_011947807.1 hypothetical protein -
OXA90_RS14705 (OXA90_14705) 3301111..3301215 - 105 Protein_2885 lytic murein transglycosylase -
OXA90_RS14710 (OXA90_14710) 3301309..3301638 - 330 Protein_2886 hypothetical protein -
OXA90_RS14715 (OXA90_14715) 3302831..3303313 - 483 WP_014842908.1 hypothetical protein -
OXA90_RS14720 (OXA90_14720) 3303402..3303698 - 297 WP_042234319.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OXA90_RS14725 (OXA90_14725) 3303688..3303939 - 252 WP_027266056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OXA90_RS14730 (OXA90_14730) 3304805..3305944 - 1140 WP_129317146.1 DUF3800 domain-containing protein -
OXA90_RS14735 (OXA90_14735) 3306062..3306619 - 558 WP_129317147.1 recombinase family protein -
OXA90_RS14740 (OXA90_14740) 3306707..3306847 + 141 WP_154231193.1 hypothetical protein -
OXA90_RS14745 (OXA90_14745) 3306872..3307375 - 504 WP_042234312.1 hypothetical protein -
OXA90_RS14750 (OXA90_14750) 3307485..3308531 - 1047 WP_027219936.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-60)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11424.29 Da        Isoelectric Point: 10.5027

>T265720 WP_042234319.1 NZ_CP113437:c3303698-3303402 [Legionella pneumophila]
MIYELHFHPLALKEWKKLGKNLQEEFKKVLKRRLENPHVASAGLRGSLKNCYKIKLRQSGYRLVYQVNDNKLIVTVIAVG
KRNKNVVYGDADNRQEDS

Download         Length: 297 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.70 Da        Isoelectric Point: 5.0359

>AT265720 WP_027266056.1 NZ_CP113437:c3303939-3303688 [Legionella pneumophila]
MQTLFATQVASISELKKNPTKLINDAHGKPVAILNHNTAAAYLIPVETFEKLMDLIDENELHKIVEERLSAPFTSIKVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References