Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2298810..2299326 Replicon chromosome
Accession NZ_CP113432
Organism Pseudomonas sp. ZM23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OU419_RS10835 Protein ID WP_254472157.1
Coordinates 2298810..2299091 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OU419_RS10840 Protein ID WP_254472158.1
Coordinates 2299081..2299326 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU419_RS10805 (OU419_10805) 2294628..2294900 + 273 WP_254472211.1 hypothetical protein -
OU419_RS10810 (OU419_10810) 2294993..2295961 + 969 WP_254472153.1 DUF932 domain-containing protein -
OU419_RS10815 (OU419_10815) 2296041..2297045 + 1005 WP_254472212.1 YqaJ viral recombinase family protein -
OU419_RS10820 (OU419_10820) 2297137..2298087 + 951 WP_254472154.1 hydrolase or metal-binding protein -
OU419_RS10825 (OU419_10825) 2298059..2298556 + 498 WP_254472155.1 DNA repair protein RadC -
OU419_RS10830 (OU419_10830) 2298567..2298740 + 174 WP_254472156.1 hypothetical protein -
OU419_RS10835 (OU419_10835) 2298810..2299091 - 282 WP_254472157.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OU419_RS10840 (OU419_10840) 2299081..2299326 - 246 WP_254472158.1 antitoxin Antitoxin
OU419_RS10845 (OU419_10845) 2299515..2300213 - 699 WP_254472159.1 inovirus Gp2 family protein -
OU419_RS10850 (OU419_10850) 2300512..2301858 - 1347 WP_254472160.1 site-specific integrase -
OU419_RS10855 (OU419_10855) 2302394..2303377 - 984 WP_254472161.1 nitronate monooxygenase -
OU419_RS10860 (OU419_10860) 2303515..2304174 - 660 WP_254472162.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2272999..2300213 27214


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10772.61 Da        Isoelectric Point: 10.6485

>T265710 WP_254472157.1 NZ_CP113432:c2299091-2298810 [Pseudomonas sp. ZM23]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLGERLEAPKVQADALRDLPGHYKIKLRTASYRLVYRVEDDRVVVMVVAVSK
RERSTAYKAAGKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8696.06 Da        Isoelectric Point: 4.1630

>AT265710 WP_254472158.1 NZ_CP113432:c2299326-2299081 [Pseudomonas sp. ZM23]
MQSVLADVAVSVSELKKNPTGVMAGAGGMPVAVLNHNRVMGYMVPAELYEQMLERLDDLDLIDVVNVRSGEKGVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References