Detailed information of TA system TA265709

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 1846543..1848020
• Replicon: chromosome
• Accession: NZ_CP113432
• Organism: Pseudomonas sp. ZM23

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OU419_RS08800
• Protein ID: WP_254476688.1
• Coordinates: 1846543..1847112 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OU419_RS08805
• Protein ID: WP_254476689.1
• Coordinates: 1847169..1848020 (+)
• Length: 284 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OU419_RS08790 (OU419_08790)	1842297..1842755	+	459	WP_254476686.1	DMT family transporter	-
OU419_RS08795 (OU419_08795)	1842794..1846270	-	3477	WP_254476687.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-
OU419_RS08800 (OU419_08800)	1846543..1847112	+	570	WP_254476688.1	GNAT family protein	Toxin
OU419_RS08805 (OU419_08805)	1847169..1848020	+	852	WP_254476689.1	AraC family transcriptional regulator	Antitoxin
OU419_RS08810 (OU419_08810)	1848221..1850386	+	2166	WP_254476690.1	TonB-dependent receptor family protein	-
OU419_RS08815 (OU419_08815)	1850547..1852421	+	1875	WP_254476691.1	MFS transporter	-
OU419_RS08820 (OU419_08820)	1852485..1852694	-	210	WP_024763416.1	cold-shock protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (197-274)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21419.70 Da
• Isoelectric Point: 10.2617

>T265709 WP_254476688.1 NZ_CP113432:1846543-1847112 [Pseudomonas sp. ZM23]
MFRPLPITLQRGALRLEPMVEADVPELVTLAEANREVLQFMSAPQRPDWYRQGLAEQRDGRALPLVVRLGNRIVGTTRFM
DFLPALPACEIGATWLDQEQHGRGLNATMKYLMLRHAFDSWKMVRVQFKTAASNQRGQRSIEKLGAVREGVLRNHRRLAG
GRLDDTILYSITDHEWPQVKAALEAGFSG

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 284 a.a.
• Molecular weight: 31338.60 Da
• Isoelectric Point: 8.3260

>AT265709 WP_254476689.1 NZ_CP113432:1847169-1848020 [Pseudomonas sp. ZM23]
MAQGNASGEKTRFWRAQELGGVELLHARYIEQVFSPHVHEGFAFVMIEQGAQRFHHRGAEHFAPSGSVVLINPDEVHTGS
KADDAGWRYRGFYPELAQVSGVLEELELGRGGTPSFDASVVFNPELVQALFAAHRLVDSDASVLQRQTCWREALLLLFQR
HARIPEAPPAGNEPVAVARARELLGSRLMEPPSLEELAAAVGLSPFHFARVFRKATGLPPHAWLKQRRLEQARALLKQGC
MPVNVATQLGFADQSHLSRQFKQAYGVGPGEYRQACARSFRSV

Nucleotide

• Length: 852 bp