Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1830326..1831456 Replicon chromosome
Accession NZ_CP113432
Organism Pseudomonas sp. ZM23

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OU419_RS08740 Protein ID WP_254476678.1
Coordinates 1830695..1831456 (+) Length 254 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OU419_RS08735 Protein ID WP_254476677.1
Coordinates 1830326..1830694 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU419_RS08700 (OU419_08700) 1825499..1826773 + 1275 WP_254476671.1 hypothetical protein -
OU419_RS08705 (OU419_08705) 1826865..1827113 + 249 WP_254476672.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OU419_RS08710 (OU419_08710) 1827121..1827462 + 342 WP_254476673.1 type II toxin-antitoxin system RelE/ParE family toxin -
OU419_RS08715 (OU419_08715) 1827855..1828259 - 405 WP_254476674.1 hypothetical protein -
OU419_RS08720 (OU419_08720) 1828329..1828670 - 342 WP_254476675.1 carboxymuconolactone decarboxylase family protein -
OU419_RS08725 (OU419_08725) 1828784..1829701 + 918 WP_254476676.1 AraC family transcriptional regulator -
OU419_RS08730 (OU419_08730) 1829695..1830177 - 483 WP_254476741.1 GreA/GreB family elongation factor -
OU419_RS08735 (OU419_08735) 1830326..1830694 + 369 WP_254476677.1 DUF2384 domain-containing protein Antitoxin
OU419_RS08740 (OU419_08740) 1830695..1831456 + 762 WP_254476678.1 RES family NAD+ phosphorylase Toxin
OU419_RS08745 (OU419_08745) 1831531..1831740 + 210 WP_254476679.1 hypothetical protein -
OU419_RS08750 (OU419_08750) 1832330..1833694 + 1365 WP_254476742.1 DNA recombination protein RmuC -
OU419_RS08755 (OU419_08755) 1833894..1835240 - 1347 WP_254476680.1 FAD-binding oxidoreductase -
OU419_RS08760 (OU419_08760) 1835331..1836221 - 891 WP_254476681.1 metal-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(65-209)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-50)


Sequences

Toxin        


Download         Length: 254 a.a.        Molecular weight: 28801.80 Da        Isoelectric Point: 6.9639

>T265708 WP_254476678.1 NZ_CP113432:1830695-1831456 [Pseudomonas sp. ZM23]
MEGAEIWARHEQDAVVGPIRGRLVRLVESQGQVATLQLVDTLEEQALLEELLETSKPRVPPSAESLHYLLKTPFRYPPLR
WGSRFGRRHEPSLFYAALKLETAMAESAYYRFVLWEGMSAPPPSGRILSEHASFEARFQVQRGVRLQLPPFSEYEAELCD
PADYRVTQGLGSSMREAGVEAFEYRSARCPQRGVNVALYAPSAFMEKRPRNLAPWLCETTAEYVAFKHGQVPDTPRVFTR
ERYLVDGRLPYPA

Download         Length: 762 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13449.75 Da        Isoelectric Point: 10.2091

>AT265708 WP_254476677.1 NZ_CP113432:1830326-1830694 [Pseudomonas sp. ZM23]
MSALLRESPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQGGLRVDSKTGELALLLVRIYRALFALFGGNL
EDMRHFLRTENRHLGGVPLQLMERVQGLVTVIEYLDAIRGKV

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References