265707

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 1826865..1827462 Replicon chromosome
Accession NZ_CP113432
Organism Pseudomonas sp. ZM23

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag OU419_RS08710 Protein ID WP_254476673.1
Coordinates 1827121..1827462 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag OU419_RS08705 Protein ID WP_254476672.1
Coordinates 1826865..1827113 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU419_RS08680 (OU419_08680) 1821940..1822182 + 243 WP_254476843.1 major capsid protein -
OU419_RS08685 (OU419_08685) 1822330..1823610 + 1281 WP_268173309.1 attachment protein -
OU419_RS08690 (OU419_08690) 1823614..1823970 + 357 WP_254476845.1 DUF2523 family protein -
OU419_RS08695 (OU419_08695) 1823974..1825263 + 1290 WP_268173310.1 zonular occludens toxin domain-containing protein -
OU419_RS08700 (OU419_08700) 1825499..1826773 + 1275 WP_254476671.1 hypothetical protein -
OU419_RS08705 (OU419_08705) 1826865..1827113 + 249 WP_254476672.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OU419_RS08710 (OU419_08710) 1827121..1827462 + 342 WP_254476673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OU419_RS08715 (OU419_08715) 1827855..1828259 - 405 WP_254476674.1 hypothetical protein -
OU419_RS08720 (OU419_08720) 1828329..1828670 - 342 WP_254476675.1 carboxymuconolactone decarboxylase family protein -
OU419_RS08725 (OU419_08725) 1828784..1829701 + 918 WP_254476676.1 AraC family transcriptional regulator -
OU419_RS08730 (OU419_08730) 1829695..1830177 - 483 WP_254476741.1 GreA/GreB family elongation factor -
OU419_RS08735 (OU419_08735) 1830326..1830694 + 369 WP_254476677.1 DUF2384 domain-containing protein -
OU419_RS08740 (OU419_08740) 1830695..1831456 + 762 WP_254476678.1 RES family NAD+ phosphorylase -
OU419_RS08745 (OU419_08745) 1831531..1831740 + 210 WP_254476679.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12908.56 Da        Isoelectric Point: 4.4676

>T265707 WP_254476673.1 NZ_CP113432:1827121-1827462 [Pseudomonas sp. ZM23]
MTILDVRFTETAVFSIQDQEEHLAEYHPAEVAAAKIDTLIDDILTRLQNAPVGYPVSRQASDLGVTRYRELNHDGYRVFY
EVYEHDNAIAVELVLRQKQDVEAALIRYCLVGI

Download         Length: 342 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9388.83 Da        Isoelectric Point: 9.5977

>AT265707 WP_254476672.1 NZ_CP113432:1826865-1827113 [Pseudomonas sp. ZM23]
MRVETISYLKRHAADLELDEPMVVTQNGVPTMVVESYAERKRRDQAIALVKLLAMGSREYTEGKHCSADELKARLAKRRT
QQ

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References