Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 66235..66740 Replicon chromosome
Accession NZ_CP113432
Organism Pseudomonas sp. ZM23

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OU419_RS00315 Protein ID WP_254469755.1
Coordinates 66235..66516 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OU419_RS00320 Protein ID WP_254469756.1
Coordinates 66513..66740 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU419_RS00290 (OU419_00290) 62140..63090 + 951 WP_254469750.1 alpha/beta hydrolase -
OU419_RS00295 (OU419_00295) 63161..64189 + 1029 WP_254469751.1 AraC family transcriptional regulator -
OU419_RS00300 (OU419_00300) 64191..64646 - 456 WP_254469752.1 GNAT family N-acetyltransferase -
OU419_RS00305 (OU419_00305) 64690..65607 - 918 WP_254469753.1 LysR family transcriptional regulator -
OU419_RS00310 (OU419_00310) 65705..65992 + 288 WP_254469754.1 DUF2218 domain-containing protein -
OU419_RS00315 (OU419_00315) 66235..66516 - 282 WP_254469755.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OU419_RS00320 (OU419_00320) 66513..66740 - 228 WP_254469756.1 CopG family ribbon-helix-helix protein Antitoxin
OU419_RS00325 (OU419_00325) 66998..68383 + 1386 WP_254469757.1 sodium:solute symporter -
OU419_RS00330 (OU419_00330) 68411..69367 + 957 WP_254469758.1 agmatinase -
OU419_RS00335 (OU419_00335) 69443..70369 + 927 WP_254469759.1 LysR family transcriptional regulator -
OU419_RS00340 (OU419_00340) 70366..71085 + 720 WP_254469760.1 phytanoyl-CoA dioxygenase family protein -
OU419_RS00345 (OU419_00345) 71089..71376 - 288 WP_254469761.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10457.92 Da        Isoelectric Point: 6.4638

>T265706 WP_254469755.1 NZ_CP113432:c66516-66235 [Pseudomonas sp. ZM23]
MSLQWTHKAAADLDAIYDHYVVLIGPEKALRAIQDIVEQVRPLMNLEQSSSGAPSEVPGVRELSIERWPYQAAFRVKGRS
VQILRIDRVDNSG

Download         Length: 282 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8421.42 Da        Isoelectric Point: 5.4508

>AT265706 WP_254469756.1 NZ_CP113432:c66740-66513 [Pseudomonas sp. ZM23]
MTTVVSFRADDALVEALDQLARATHRDRPYHLRQALAQYLERQSWHVATIDEGVADADAGHLLEHTVIEAKWGLA

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References