Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 809433..810093 Replicon chromosome
Accession NZ_CP113364
Organism Salmonella enterica subsp. enterica strain KNP01

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag OU685_RS03925 Protein ID WP_000244755.1
Coordinates 809680..810093 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OU685_RS03920 Protein ID WP_000351186.1
Coordinates 809433..809699 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU685_RS03900 (805362) 805362..806795 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
OU685_RS03905 (806953) 806953..807264 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
OU685_RS03910 (807428) 807428..808087 + 660 WP_000250289.1 hemolysin III family protein -
OU685_RS03915 (808203) 808203..809183 - 981 WP_017441090.1 tRNA-modifying protein YgfZ -
OU685_RS03920 (809433) 809433..809699 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OU685_RS03925 (809680) 809680..810093 + 414 WP_000244755.1 protein YgfX Toxin
OU685_RS03930 (810146) 810146..810667 - 522 WP_017441091.1 flavodoxin FldB -
OU685_RS03935 (810780) 810780..811676 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
OU685_RS03940 (811700) 811700..812413 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OU685_RS03945 (812419) 812419..814152 + 1734 WP_000813392.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T265682 WP_000244755.1 NZ_CP113364:809680-810093 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT265682 WP_000351186.1 NZ_CP113364:809433-809699 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References