Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1157624..1158144 Replicon chromosome
Accession NZ_CP113343
Organism Arthrobacter sp. MMS18-M83

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OW521_RS05520 Protein ID WP_268023615.1
Coordinates 1157887..1158144 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OW521_RS05515 Protein ID WP_268023613.1
Coordinates 1157624..1157890 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OW521_RS05495 (OW521_05495) 1153071..1153829 - 759 Protein_1082 tyrosine-protein phosphatase -
OW521_RS05500 (OW521_05500) 1154032..1154373 + 342 WP_268023609.1 YciI family protein -
OW521_RS05505 (OW521_05505) 1154414..1156153 - 1740 WP_268023610.1 HNH endonuclease signature motif containing protein -
OW521_RS05510 (OW521_05510) 1156289..1157476 + 1188 WP_268023611.1 hypothetical protein -
OW521_RS05515 (OW521_05515) 1157624..1157890 + 267 WP_268023613.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OW521_RS05520 (OW521_05520) 1157887..1158144 + 258 WP_268023615.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OW521_RS05525 (OW521_05525) 1158214..1159629 - 1416 WP_268023617.1 NAD(P)H-quinone dehydrogenase -
OW521_RS05530 (OW521_05530) 1159757..1160575 + 819 WP_268023619.1 purine-nucleoside phosphorylase -
OW521_RS05535 (OW521_05535) 1160782..1161387 + 606 WP_268023621.1 hypothetical protein -
OW521_RS05540 (OW521_05540) 1161506..1162237 + 732 WP_268023623.1 YcnI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9896.62 Da        Isoelectric Point: 11.7454

>T265678 WP_268023615.1 NZ_CP113343:1157887-1158144 [Arthrobacter sp. MMS18-M83]
VRYNVVVLPAALRQLRKLPPEARRRIQAAIELLAETPRPPGAKKLTGRVEWRVRTGDYRVLYRIDDGRLVIVVVQAGHRR
EVYRE

Download         Length: 258 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10032.25 Da        Isoelectric Point: 4.3158

>AT265678 WP_268023613.1 NZ_CP113343:1157624-1157890 [Arthrobacter sp. MMS18-M83]
MTDIAITEARNHLATIVDTAHREHEPVFLTRRGIRVAAVIDSAELERLREAAEELEDIRAVDLAWEEMEQTGQTPIPWED
VKRDLGLT

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References