Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 288709..289340 Replicon chromosome
Accession NZ_CP113264
Organism Streptomonospora nanhaiensis strain 12A09

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OUQ99_RS01360 Protein ID WP_267947586.1
Coordinates 288709..289122 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OUQ99_RS01365 Protein ID WP_267947587.1
Coordinates 289119..289340 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OUQ99_RS01340 (OUQ99_01340) 284408..285115 - 708 WP_267950211.1 WbqC family protein -
OUQ99_RS01345 (OUQ99_01345) 285510..287048 + 1539 WP_267947583.1 glycosyltransferase -
OUQ99_RS01350 (OUQ99_01350) 287177..287587 + 411 WP_267947584.1 DUF3817 domain-containing protein -
OUQ99_RS01355 (OUQ99_01355) 287563..288351 - 789 WP_267947585.1 SURF1 family protein -
OUQ99_RS01360 (OUQ99_01360) 288709..289122 - 414 WP_267947586.1 PIN domain-containing protein Toxin
OUQ99_RS01365 (OUQ99_01365) 289119..289340 - 222 WP_267947587.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OUQ99_RS01370 (OUQ99_01370) 289440..289973 - 534 WP_267947588.1 DinB family protein -
OUQ99_RS01375 (OUQ99_01375) 290129..290896 + 768 WP_267947589.1 alpha/beta fold hydrolase -
OUQ99_RS01380 (OUQ99_01380) 290998..291405 - 408 WP_267947590.1 VOC family protein -
OUQ99_RS01385 (OUQ99_01385) 291629..292291 - 663 WP_267947591.1 class II aldolase/adducin family protein -
OUQ99_RS01390 (OUQ99_01390) 292613..294139 + 1527 WP_267947592.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(4-44)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15669.57 Da        Isoelectric Point: 6.9177

>T265669 WP_267947586.1 NZ_CP113264:c289122-288709 [Streptomonospora nanhaiensis]
VIRYLIDSSALWRVLRDPKHRDAWRDVVVEGAVGSCAVQRTEFRRSARNLDEYEQFNEMFETLHPDVPTPKSAWQWVESA
QYRLLRGGAHRAMSSVDLLIAATAAHHGLVVLHDDNDFATAAHHLTDLRERSVRNTP

Download         Length: 414 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8408.35 Da        Isoelectric Point: 6.4699

>AT265669 WP_267947587.1 NZ_CP113264:c289340-289119 [Streptomonospora nanhaiensis]
MSLTQVDIDDEALREAMRLSGASTKKETVNLALREYAARHRRIAALEHFSALARDWDYESWQKRRSAEKGDGE

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References