Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 162057..162597 Replicon chromosome
Accession NZ_CP113241
Organism Vibrio sp. gvc

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OOK74_RS00725 Protein ID WP_278182918.1
Coordinates 162057..162326 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OOK74_RS00730 Protein ID WP_278182919.1
Coordinates 162319..162597 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOK74_RS00705 157354..158265 + 912 WP_278182914.1 glycosyltransferase -
OOK74_RS00710 158262..159176 + 915 WP_278182915.1 NAD-dependent epimerase/dehydratase family protein -
OOK74_RS00715 159173..159721 + 549 WP_278182916.1 sugar transferase -
OOK74_RS00720 159949..161904 + 1956 WP_278182917.1 nucleoside-diphosphate sugar epimerase/dehydratase -
OOK74_RS00725 162057..162326 - 270 WP_278182918.1 type II toxin-antitoxin system YafQ family toxin Toxin
OOK74_RS00730 162319..162597 - 279 WP_278182919.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OOK74_RS00735 162786..162959 + 174 WP_278182920.1 Txe/YoeB family addiction module toxin -
OOK74_RS00740 163209..163703 + 495 WP_278182921.1 DUF1456 family protein -
OOK74_RS00745 163824..164060 - 237 WP_166013882.1 RNA-binding protein -
OOK74_RS00750 164333..165685 + 1353 WP_278182922.1 MBL fold metallo-hydrolase -
OOK74_RS00755 166187..166414 + 228 WP_274723261.1 Flp family type IVb pilin -
OOK74_RS00760 166383..166844 + 462 WP_274723292.1 prepilin peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10455.19 Da        Isoelectric Point: 9.6284

>T265644 WP_278182918.1 NZ_CP113241:c162326-162057 [Vibrio sp. gvc]
MFKLEYSTQFKKDFKKITRMPISDIIEVGHVISKLQRGEKLEPKNVDHPLTGNWVGFRDCHIKPDLVLIYRVFNEQLQLA
RLGSHSDLF

Download         Length: 270 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10101.62 Da        Isoelectric Point: 6.4788

>AT265644 WP_278182919.1 NZ_CP113241:c162597-162319 [Vibrio sp. gvc]
MRTEMLSTRIDHDTKIAFTNVCNEMGLSTSQAIKLFAKAVINHGGIPFELRVPQPNEVTASAIQELVEGKAHKAESVEAM
LNELTEGKVKHV

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References