265638

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 438553..439030 Replicon chromosome
Accession NZ_CP113231
Organism Staphylococcus aureus strain BIAI 158

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag OSZ57_RS02145 Protein ID WP_000052076.1
Coordinates 438553..438741 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag OSZ57_RS02150 Protein ID WP_001059690.1
Coordinates 438770..439030 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSZ57_RS02115 (434543) 434543..435064 + 522 WP_000824479.1 hypothetical protein -
OSZ57_RS02120 (435405) 435405..436091 + 687 WP_001622483.1 thermonuclease family protein -
OSZ57_RS02125 (436448) 436448..436648 + 201 WP_001059082.1 cold-shock protein -
OSZ57_RS02130 (437145) 437145..437363 - 219 WP_000005884.1 hypothetical protein -
OSZ57_RS02135 (437436) 437436..437708 - 273 WP_001004400.1 hypothetical protein -
OSZ57_RS02140 (437796) 437796..438365 - 570 WP_001106662.1 lipoprotein N-acylation protein LnsA -
OSZ57_RS02145 (438553) 438553..438741 - 189 WP_000052076.1 hypothetical protein Toxin
OSZ57_RS02150 (438770) 438770..439030 - 261 WP_001059690.1 hypothetical protein Antitoxin
OSZ57_RS02155 (439371) 439371..439574 + 204 WP_000145160.1 sterile alpha motif-like domain-containing protein -
OSZ57_RS02160 (439571) 439571..439807 - 237 WP_000368687.1 hypothetical protein -
OSZ57_RS02165 (440031) 440031..440612 + 582 WP_001140696.1 histidine phosphatase family protein -
OSZ57_RS02170 (440685) 440685..441302 - 618 WP_000255550.1 LysE/ArgO family amino acid transporter -
OSZ57_RS02175 (441458) 441458..441952 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
OSZ57_RS02180 (442351) 442351..442773 - 423 WP_000974451.1 organic hydroperoxide resistance protein -
OSZ57_RS02185 (442921) 442921..443637 + 717 WP_000150033.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T265638 WP_000052076.1 NZ_CP113231:c438741-438553 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT265638 WP_001059690.1 NZ_CP113231:c439030-438770 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References