Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1950577..1950722 Replicon chromosome
Accession NZ_CP113216
Organism Klebsiella pneumoniae strain SCLC9-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1950613..1950715 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1950577..1950722 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OT489_RS09645 1945707..1947767 + 2061 WP_004151449.1 oligopeptidase B -
OT489_RS09650 1947771..1948430 - 660 WP_032425085.1 exodeoxyribonuclease X -
OT489_RS09655 1948509..1948739 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OT489_RS09660 1948852..1949226 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OT489_RS09665 1949230..1950099 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
OT489_RS09670 1950116..1950454 + 339 WP_016529031.1 YebY family protein -
- 1950577..1950722 - 146 - - Antitoxin
- 1950613..1950715 + 103 - - Toxin
OT489_RS09675 1951090..1951233 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OT489_RS09680 1951338..1952306 - 969 WP_004151446.1 VirK/YbjX family protein -
OT489_RS09685 1952463..1953116 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OT489_RS09690 1953113..1953304 - 192 WP_002911395.1 YebW family protein -
OT489_RS09695 1953402..1953641 - 240 WP_002911393.1 YebV family protein -
OT489_RS09700 1953757..1955190 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265611 NZ_CP113216:1950613-1950715 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT265611 NZ_CP113216:c1950722-1950577 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References