Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867458..1867603 Replicon chromosome
Accession NZ_CP113211
Organism Klebsiella pneumoniae strain SYCC22-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1867494..1867596 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867458..1867603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OT491_RS09150 1862588..1864648 + 2061 WP_004151449.1 oligopeptidase B -
OT491_RS09155 1864652..1865311 - 660 WP_002911407.1 exodeoxyribonuclease X -
OT491_RS09160 1865390..1865620 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OT491_RS09165 1865733..1866107 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OT491_RS09170 1866111..1866980 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OT491_RS09175 1866997..1867335 + 339 WP_002911404.1 YebY family protein -
- 1867458..1867603 - 146 - - Antitoxin
- 1867494..1867596 + 103 - - Toxin
OT491_RS09180 1867971..1868114 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OT491_RS09185 1868219..1869187 - 969 WP_004151446.1 VirK/YbjX family protein -
OT491_RS09190 1869344..1869997 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
OT491_RS09195 1869994..1870185 - 192 WP_002911395.1 YebW family protein -
OT491_RS09200 1870283..1870522 - 240 WP_002911393.1 YebV family protein -
OT491_RS09205 1870638..1872071 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265593 NZ_CP113211:1867494-1867596 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT265593 NZ_CP113211:c1867603-1867458 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References