Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1867466..1867611 | Replicon | chromosome |
| Accession | NZ_CP113202 | ||
| Organism | Klebsiella pneumoniae strain SCLC4-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1867502..1867604 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1867466..1867611 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OT485_RS09150 | 1862596..1864656 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| OT485_RS09155 | 1864660..1865319 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| OT485_RS09160 | 1865398..1865628 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| OT485_RS09165 | 1865741..1866115 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| OT485_RS09170 | 1866119..1866988 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| OT485_RS09175 | 1867005..1867343 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1867466..1867611 | - | 146 | - | - | Antitoxin |
| - | 1867502..1867604 | + | 103 | - | - | Toxin |
| OT485_RS09180 | 1867979..1868122 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| OT485_RS09185 | 1868227..1869195 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| OT485_RS09190 | 1869352..1870005 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| OT485_RS09195 | 1870002..1870193 | - | 192 | WP_002911395.1 | YebW family protein | - |
| OT485_RS09200 | 1870291..1870530 | - | 240 | WP_002911393.1 | YebV family protein | - |
| OT485_RS09205 | 1870646..1872079 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T265577 NZ_CP113202:1867502-1867604 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT265577 NZ_CP113202:c1867611-1867466 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT