Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867466..1867611 Replicon chromosome
Accession NZ_CP113202
Organism Klebsiella pneumoniae strain SCLC4-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1867502..1867604 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867466..1867611 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OT485_RS09150 1862596..1864656 + 2061 WP_004151449.1 oligopeptidase B -
OT485_RS09155 1864660..1865319 - 660 WP_002911407.1 exodeoxyribonuclease X -
OT485_RS09160 1865398..1865628 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OT485_RS09165 1865741..1866115 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OT485_RS09170 1866119..1866988 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OT485_RS09175 1867005..1867343 + 339 WP_002911404.1 YebY family protein -
- 1867466..1867611 - 146 - - Antitoxin
- 1867502..1867604 + 103 - - Toxin
OT485_RS09180 1867979..1868122 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OT485_RS09185 1868227..1869195 - 969 WP_004151446.1 VirK/YbjX family protein -
OT485_RS09190 1869352..1870005 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
OT485_RS09195 1870002..1870193 - 192 WP_002911395.1 YebW family protein -
OT485_RS09200 1870291..1870530 - 240 WP_002911393.1 YebV family protein -
OT485_RS09205 1870646..1872079 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265577 NZ_CP113202:1867502-1867604 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT265577 NZ_CP113202:c1867611-1867466 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References