Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3260324..3260469 Replicon chromosome
Accession NZ_CP113191
Organism Klebsiella pneumoniae strain SYCC2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3260331..3260433 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3260324..3260469 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OT482_RS18810 3255855..3257288 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OT482_RS18815 3257404..3257643 + 240 WP_002911393.1 YebV family protein -
OT482_RS18820 3257741..3257932 + 192 WP_002911395.1 YebW family protein -
OT482_RS18825 3257929..3258582 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OT482_RS18830 3258739..3259707 + 969 WP_004151446.1 VirK/YbjX family protein -
OT482_RS18835 3259812..3259955 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3260324..3260469 + 146 - - Antitoxin
- 3260331..3260433 - 103 - - Toxin
OT482_RS18840 3260592..3260930 - 339 WP_002911404.1 YebY family protein -
OT482_RS18845 3260947..3261816 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OT482_RS18850 3261820..3262194 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OT482_RS18855 3262307..3262537 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OT482_RS18860 3262616..3263275 + 660 WP_020324964.1 exodeoxyribonuclease X -
OT482_RS18865 3263279..3265339 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265533 NZ_CP113191:c3260433-3260331 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT265533 NZ_CP113191:3260324-3260469 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References