Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966252..1966397 Replicon chromosome
Accession NZ_CP113173
Organism Klebsiella pneumoniae strain TSYCC10-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966288..1966390 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966252..1966397 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OT486_RS09735 1961382..1963442 + 2061 WP_004151449.1 oligopeptidase B -
OT486_RS09740 1963446..1964105 - 660 WP_002911407.1 exodeoxyribonuclease X -
OT486_RS09745 1964184..1964414 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OT486_RS09750 1964527..1964901 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OT486_RS09755 1964905..1965774 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
OT486_RS09760 1965791..1966129 + 339 WP_002911404.1 YebY family protein -
- 1966252..1966397 - 146 - - Antitoxin
- 1966288..1966390 + 103 - - Toxin
OT486_RS09765 1966765..1966908 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OT486_RS09770 1967013..1967981 - 969 WP_004151446.1 VirK/YbjX family protein -
OT486_RS09775 1968138..1968791 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OT486_RS09780 1968788..1968979 - 192 WP_002911395.1 YebW family protein -
OT486_RS09785 1969077..1969316 - 240 WP_002911393.1 YebV family protein -
OT486_RS09790 1969432..1970865 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T265485 NZ_CP113173:1966288-1966390 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT265485 NZ_CP113173:c1966397-1966252 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References