Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1972989..1973134 | Replicon | chromosome |
| Accession | NZ_CP113168 | ||
| Organism | Klebsiella pneumoniae strain TSNTC34-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1973025..1973127 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1972989..1973134 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OT488_RS09515 | 1968119..1970179 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| OT488_RS09520 | 1970183..1970842 | - | 660 | WP_087616344.1 | exodeoxyribonuclease X | - |
| OT488_RS09525 | 1970921..1971151 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| OT488_RS09530 | 1971264..1971638 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| OT488_RS09535 | 1971642..1972511 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| OT488_RS09540 | 1972528..1972866 | + | 339 | WP_004189269.1 | YebY family protein | - |
| - | 1972989..1973134 | - | 146 | - | - | Antitoxin |
| - | 1973025..1973127 | + | 103 | - | - | Toxin |
| OT488_RS09545 | 1973501..1973644 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| OT488_RS09550 | 1973749..1974717 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| OT488_RS09555 | 1974874..1975527 | + | 654 | WP_004189273.1 | protein-serine/threonine phosphatase | - |
| OT488_RS09560 | 1975524..1975715 | - | 192 | WP_002911395.1 | YebW family protein | - |
| OT488_RS09565 | 1975813..1976052 | - | 240 | WP_002911393.1 | YebV family protein | - |
| OT488_RS09570 | 1976168..1977601 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T265469 NZ_CP113168:1973025-1973127 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT265469 NZ_CP113168:c1973134-1972989 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
