265443

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4559569..4560223 Replicon chromosome
Accession NZ_CP113163
Organism Citrobacter braakii strain LBA3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MKJ05_RS21780 Protein ID WP_114681070.1
Coordinates 4559816..4560223 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID R8WMJ6
Locus tag MKJ05_RS21775 Protein ID WP_016154349.1
Coordinates 4559569..4559835 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKJ05_RS21750 (MKJ05_21750) 4554782..4556215 - 1434 WP_267588330.1 6-phospho-beta-glucosidase BglA -
MKJ05_RS21755 (MKJ05_21755) 4556336..4557064 - 729 WP_003838265.1 MurR/RpiR family transcriptional regulator -
MKJ05_RS21760 (MKJ05_21760) 4557117..4557428 + 312 WP_114681074.1 N(4)-acetylcytidine aminohydrolase -
MKJ05_RS21765 (MKJ05_21765) 4557592..4558251 + 660 WP_114681073.1 hemolysin III family protein -
MKJ05_RS21770 (MKJ05_21770) 4558331..4559311 - 981 WP_267588331.1 tRNA-modifying protein YgfZ -
MKJ05_RS21775 (MKJ05_21775) 4559569..4559835 + 267 WP_016154349.1 FAD assembly factor SdhE Antitoxin
MKJ05_RS21780 (MKJ05_21780) 4559816..4560223 + 408 WP_114681070.1 protein YgfX Toxin
MKJ05_RS21785 (MKJ05_21785) 4560324..4560845 - 522 WP_199143062.1 flavodoxin FldB -
MKJ05_RS21790 (MKJ05_21790) 4560958..4561854 + 897 WP_103766659.1 site-specific tyrosine recombinase XerD -
MKJ05_RS21795 (MKJ05_21795) 4561878..4562591 + 714 WP_114681068.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MKJ05_RS21800 (MKJ05_21800) 4562597..4564330 + 1734 WP_267588332.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15924.80 Da        Isoelectric Point: 11.2845

>T265443 WP_114681070.1 NZ_CP113163:4559816-4560223 [Citrobacter braakii]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDVGKRQHLWLAADSMDDAEWRDLRRLILQQAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.10 Da        Isoelectric Point: 5.6375

>AT265443 WP_016154349.1 NZ_CP113163:4559569-4559835 [Citrobacter braakii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB R8WMJ6

References